Hannah Mbatia

From BurdetteLab

Hannah W. Mbatia

Bachelor's Institution: University of Nairobi
Bachelor's Year: 2005
Ph.D. Institution: UConn
Ph.D. Year: 2012
Postdoc Institution: UMB Medicine
Postdoc Years: 2012–2015
Current Employer: Senseonics

Hannah W. Mbatia is a former student in the Burdette group, and the 2nd person to earn a Ph.D. under the the supervision of Prof. Shawn Burdette. She graduated with a chemistry degree from University of Nairobi in 2005, and received his Ph.D. in 2012 from University of Connecticut.

Hannah's profile on LinkedIn.

Major Accomplishments






ArgenCast Analogues


Synthetic Methodology



9. Vincent Njar, Hannah Mbatia, Vidya Ramamurthy and Senthilmurugan Ramalingam. 2016, Patent:13-cis-Ramba Retinamides That Degrade mnks for Treating Cancer

8. Hannah W. Mbatia, Senthilmurugan Ramalingam, Vidya P. Ramamurthy, Marlena S. Martin, Andrew K. Kwegyir-Afful, and Vincent C. O. Njar. J. Med. Chem. 2015, 58, 1900–1914. Novel C-4 Heteroaryl 13-cis-Retinamide Mnk/AR Degrading Agents Inhibit Cell Proliferation and Migration and Induce Apoptosis in Human Breast and Prostate Cancer Cells and Suppress Growth of MDA-MB-231 Human Breast and CWR22Rv1 Human Prostate Tumor Xenografts in Mice

7. Abhijit M. Godbole, Senthilmurugan Ramalingam, Vidya P. Ramamurthy, Aakanksha Khandelwal, Robert D. Bruno, Vijay V. Upreti, Lalji K. Gediya, Puranik Purushottamachar, Hannah W. Mbatia, Sankar Addya, Nicholas Ambulos and Vincent C.O. Njar. Eur. J. Pharmacol. 2014, 734, 98–104. VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats

6. Senthilmurugan Ramalingam, Lalji Gediya, Andrew K. Kwegyir-Afful, Vidya P. Ramamurthy, Puranik Purushottamachar, Hannah Mbatia and Vincent C. O. Njar. Oncotarget. 2014, 5, 530–543.First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

5. Hannah W. Mbatia and Shawn C. Burdette. Biochemistry 2012, 51, 7212–7224. Photochemical Tools for Studying Metal Ion Signaling and Homeostasis. Article is a Current Topics feature.

4. Hannah W. Mbatia, H. M. Dhammika Bandara and Shawn C. Burdette. Chem. Commun. 2012, 48, 5331–5333. CuproCleav-1, a first generation photocage for Cu+.

3. Hannah W. Mbatia, Daniel P. Kennedy and Shawn C. Burdette. Photochem. Photobiol. 2012, 88, 844–850. Understanding Relationship Between Photolysis Efficiency and Metal Binding Using ArgenCast Photocages.

2. Hannah W. Mbatia, Olbelina A. Ulloa, Daniel P. Kennedy, Christopher D. Incarvito and Shawn C. Burdette. Org. Biomol. Chem. 2011, 9, 2987–2991. Iodination of anilines and phenols with 18-crown-6 supported ICl2.

1. Hannah W. Mbatia, Daniel P. Kennedy, Casey E. Camire, Christopher D. Incarvito and Shawn C. Burdette. Eur. J. Inorg. Chem. 2010, 5069–5078. Buffering Heavy Metal Ions with Photoactive CrownCast Cages.