FerriCast-1

FerriCast-1 Architect: Daniel Kennedy Year Reported: 2010 Journal Reference: Inorg. Chem. 49, 916

FerriCast-1 is a Cast-type photocage that was developed by Daniel Kennedy and inspired by fluorescent sensor for Fe³⁺ reported by Rurack. The receptor is a N₂SO macrocyclic ligand. FerriCast-1 binds Fe³⁺ selectively in non-aqueous solution, but contrary to earlier reports the NS₂O cannot bind Fe³⁺ in aqueous solution. Subsequent analysis suggest the fluorescence studies showed a fluorescence response to protons not Fe³⁺. The photolysis of FerriCast-1 results in the introduction of an electron withdrawing carbonyl group para to the aniline that decreases the electron density on nitrogen atom and therefore the Fe³⁺ affinity.

X-ray Structure of FerriCast model ligand with Cu+. Cu+ results from the reduction of Cu2+ by the ligand in CH3CN