ZinCleav-1
From BurdetteLab
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| Architect: | Dhammika Bandara |
| Year Reported: | 2009 |
| Journal Reference: | Inorg. Chem. 48, 8445 |
ZinCleav-1 is a Cleav-type photocage that was developed by Dhammika Bandara with the assistance of Daniel Kennedy and Elif Akin. The receptor is a tetradendate chelator that incorporates two amino nitrogen donors and two pyridine ligands. ZinCleav-1 has an ~1 pM affinity for Zn2+ that decreases to ~mM in aqueous solution after photolysis. The photolysis results in the cleavage of a nitrogen-carbon bond, which fragments the ligand into two pieces.
