CrownCast-2

CrownCast-2 Architect: Daniel Kennedy/Hannah Mbatia Year Reported: 2010 Journal Reference: Eur. J. Inorg. Chem. 2010, 5069

CrownCast-2 is a Cast-type photocage that was developed by Hannah Mbatia with the assistance of Daniel Kennedy and Casey Camire. The receptor is an 18-C-6 macrocyclic azacrown ether ligand. CrownCast-2 binds an array of M²⁺ ions non-aqueous solution, and Pb²⁺ in aqueous solution. The photolysis results in the introduction of an electron withdrawing carbonyl group para to the aniline that decreases the electron density on nitrogen atom and therefore the M²⁺ affinity; however, very minimal changes are observed with in the affinity to Pb²⁺. PbSensor-1 was prepared to demonstrate Pb²⁺ decreases upon photolysis despite the metal binding data acquired by UV-vis spectroscopy.